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CAR-T Cells

As a mechanism to avoid the immune response, cancer cells suppress
the expression of MHC molecules that are essential for T cells to recognize antigens.
Recently, to overcome these problems, research has been conducted to artificially
introduce chimeric antigen receptor (CAR) which allows direct recognition
of a specific cancer without presenting antigens of MHC molecules in the T cell.
CAR is made up of proteins that can directly recognize specific cancers, thus providing personalized
medicine. In addition, CAR-T cells are safer than conventional anticancer drugs
because they are produced by introducing CAR gene after extracting patient's own T cells.

CAR-T Cells(아래설명참조)
T Cell-Cancer specific Chimeric antigen receptor in T Cell
Cancer specific Chimeric Antigen Receptor(CAR)
Cancer Cell
Cancer specific antigen
환자혈액채취→CD3 T cell 배양→암 특이적 항체수용체 발현할 DNA정보 합성→DNA치환→전사 및 단백질 발현→암 특이적 항원 수용체가 장착된 T cell(CAR-T) 배양→CAR-T 면역세포치료제 투여